NAD+500- COLLAGEN MAGICDescription NAD+ Nicotinamide adenine dinucleotide (NAD+) was discovered more than a century ago by Sir Arthur Harden as a low molecular weight substance present in a boiled yeast extract, which could stimulate fermentation and alcohol production in vitro. Subsequent studies over the next several decades determined that the structure of NAD comprised two covalently joined mononucleotides (nicotinamide mononucleotide or NMN, and AMP), and identified