Wegovy side effects timeline: what to expect week by week Healthwave If you're taking Zepbound and using oral birth control pills, there's an important interaction to be aware of. Always discuss medication interactions and contraceptive choices with your healthcare provider. Save this post Zepbound website says 2.5 for 4 wks and then to 5? : r Zepbound New clinical trial: Zepbound (tirzepatide) helped adults lose an average of 20.2% of their body weightaround 50 lbsover 72 weeks, outperforming Wegovy's 13.7% (~33 lbs). Credit to: https: www.healthline.com health news zepbound wegovy weight loss